PROLOGUE
British Diabetic Association recommended the use of the term prediabetes only in retrospect in the life of a diabetic before diabetes. WHO replaced this term in 1980’s with statistical risk classes- IGT (Impaired Glucose Tolerance), IFG (Impaired Fasting Glucose). US Secretary of Health Mr.TG Thomson reintroduced the term prediabetes in 2002 & subsequently accepted by ADA and Department of Health and Human Services USA.
DEFINITION
Prediabetes includes persons having IGT (Impaired Glucose Tolerance), IFG (Impaired Fasting Glucose) either isolated or in combination.
• Prediabetes – a condition that raises a person’s risk of developing Type 2 Diabetes, Heart Disease & Stroke. (DHHS US)
• ADA (American Diabetic Association) Practice Guidelines for diagnosis of prediabetes-
1 FBG: 100 – 125 mg/dl
2 OGT: 140 – 199 mg/dl (Oral Glucose Tolerance)
OGTT & PREDIABETES
STATE FPG Level (mg/dl) 2-h plasma glucose in OGTT (mg/dl)
IFG 100-125 <200
Isolated IFG 100-125 <140>IGT <126>
Isolated IGT <100FPG = Fasting Plasma Glucose OGTT = Oral Glucose Tolerance Test]
FALLACY OF THE TERM PREDIABETES
According to Dr. George Alberti at International Congress on Prediabetes 2005, the term “prediabetes” has some serious fallacy as noted below:
Only 50% prediabetics develop diabetes in 10 years.--- so 50% escapes.
The definition does not include some people at risk of developing diabetes– like those with strong family history, other normoglycemic risk group, and some ethnic groups.
Difficulty of communicating to general public about a high-risk situation.
PREVALENCE OF PREDIABETES IN INDIANS
South India: 14% have IGT (A. Ramchandran; BMJ 1988)
Prevalence of IGT & IFG are high in India and expected to increase from 85.6 million (2003) to 132 million (by 2025) (A. Ramchandran; Netaji Oration 2005)
IGT occurs early in Indians. (A. Ramchandran; Netaji Oration 2005)
Favourite sites for healthy lifestyle
Friday, January 30, 2009
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment